Persistence of Staphylococcus aureus strains among cystic fibrosis patients over extended periods of time

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[Methicillin-resistant Staphylococcus aureus in patients with cystic fibrosis].

OBJECTIVE To determine the prevalence of chronic colonization with methicillin-resistant Staphylococcus aureus (MRSA) in patients with cystic fibrosis, describe antibiotic sensitivity of the strains, and compare the patients' clinical characteristics with those of patients infected with methicillin-sensitive S. aureus (MSSA). PATIENTS AND METHODS Patients with chronic S. aureus colonization w...

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Emergence and spread of worldwide Staphylococcus aureus clones among cystic fibrosis patients

Background The aim of this study was to assess the relatedness of molecular types of Staphylococcus aureus isolates colonizing cystic fibrosis (CF) patients with their antimicrobial resistance and prevalence of toxin genes. Methods A total of 215 isolates from the airways of 107 patients with CF were tested for spa and SCCmec type, antimicrobial resistance and carriage of toxin genes. Resul...

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Dynamic in vivo mutations within the ica operon during persistence of Staphylococcus aureus in the airways of cystic fibrosis patients

Cystic fibrosis (CF) is associated with chronic bacterial airway infections leading to lung insufficiency and decreased life expectancy. Staphylococcus aureus is one of the most prevalent pathogens isolated from the airways of CF patients. Mucoid colony morphology has been described for Pseudomonas aeruginosa, the most common pathogen in CF, but not for S. aureus. From the airways of 8 of 313 C...

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Editorials Treatment of Staphylococcus aureus in cystic fibrosis

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ژورنال

عنوان ژورنال: Journal of Medical Microbiology

سال: 1996

ISSN: 0022-2615,1473-5644

DOI: 10.1099/00222615-45-4-294